Enzyme encapsulation in metal–organic frameworks for applications in catalysis. Issue 29 (20th February 2017)

• Record Type: Journal Article
• Authors: Majewski, Marek B.; Howarth, Ashlee J.; Li, Peng; Wasielewski, Michael R.; Hupp, Joseph T.; Farha, Omar K.
• Is Part Of: CrystEngComm. Volume 19:Issue 29(2017)
• Page Start: 4082
• Page End: 4091
• Publication Date: 2017-02-20
• Subjects: Crystals -- Periodicals; Crystal growth -- Periodicals; Crystallography -- Periodicals; Cristaux -- Périodiques; Cristaux -- Croissance -- Périodiques; Cristallographie -- Périodiques; 548
• DOI: 10.1039/c7ce00022g
• Languages: English
• ISSNs: 1466-8033

Abstract

Abstract : Various methods for encapsulating enzymes in metal–organic frameworks are discussed and the catalytic activity of biocomposites prepared using these methods is highlighted. Abstract : Enzymes are natural catalysts which are highly selective and efficient. Given that enzymes have very intricate and delicate structures, they need to be stabilized and protected by a support material if they are to be used under challenging catalytic conditions. This highlight focuses on the use of metal–organic frameworks as supports for enzyme encapsulation and subsequent catalytic applications. De novo and post-synthetic methods of encapsulation are discussed and the relative catalytic activities of the enzyme@MOF composites versus free enzymes are highlighted.