A prospective study to validate the Polish language version of the European Organisation for Research and Treatment of Cancer (EORTC) Colorectal Liver Metastases (QLQ-LMC21) module. (August 2017)

• Record Type: Journal Article
• Authors: Paradowska, Dominika; Bereza, Krzysztof; Sanna, Beatrice; Kucharska, Ewa; Tomaszewska, Iwona M.; Dudkiewicz, Zbigniew; Skotnicki, Piotr; Bottomley, Andrew; Tomaszewski, Krzysztof A.
• Is Part Of: European journal of oncology nursing. Volume 29(2017)
• Page Start: 148
• Page End: 154
• Publication Date: 2017-08
• Subjects: Colorectal cancer -- EORTC -- Hepatectomy -- Liver metastasis -- QLQ-C30 -- QLQ-LMC21 -- Quality of life -- Validation; Cancer -- Nursing -- Periodicals; Cancer -- Research -- Periodicals; Oncology -- Periodicals; Oncology Nursing -- Periodicals; Neoplasms -- nursing -- Periodicals; Cancer -- Soins infirmiers -- Périodiques; Cancer -- Recherche -- Périodiques; Cancérologie -- Périodiques; Verpleegkunde; Kanker; Cancer -- Nursing; Cancer -- Research; Oncology; Electronic journals; Periodicals; Electronic journals; 616.9940231
• DOI: 10.1016/j.ejon.2017.05.006
• Languages: English
• ISSNs: 1462-3889

Abstract

Abstract: Purpose: This validation study was designed to assess the psychometric validity and quality of the Polish translation of the EORTC QLQ-LMC21 questionnaire in Polish colorectal patients suffering with liver metastases. Methods: Patients with either histopathological or imaging confirmation of colorectal cancer with liver metastases, with a minimum of three months survival, were eligible for this study. These patients completed the Polish version of the EORTC core QLQ-C30, the QLQ-LMC21 module, and a demographic data questionnaire. The questionnaires were completed twice, once before undergoing either hepatectomy (n = 63) or palliative treatment (n = 97) and three months after the primary treatment. Standardized analyses of validity and reliability were performed. Results: One hundred and sixty patients were enrolled in this study with the mean age of the hepatectomy group 64.3 ± 14.1 and 66.1 ± 12.7 for the palliative treatment group. The QLQ-LMC21 exhibited positive internal consistency with Cronbach's alpha coefficients ranging from 0.72 to 0.90. The multi-trait scaling analysis demonstrated adequate convergent and discriminant validity. Test-retest reliability was undertaken with 40 patients (25%) with the ICCs for each item ranging from 0.64 to 0.88. The hepatectomy group had a significantly greater Karnofsky Performance Score than the palliative treatment group (p.<0.001). Overall there were weak correlations between the two questionnaires which confirm that the QLQ-LMC21 addresses health issues not assessed in the QLQ-C30. Conclusion: The Polish version of the QLQ-LMC21 proved to be a valid and reliable questionnaire to use in conjunction with the QLQ-C30 core questionnaire. Highlights: EORTC QLQ-LMC21 questionnaire in Polish colorectal patients was assessed. The Polish translation had a positive internal consistency. The multi-trait scaling analysis demonstrated acceptable convergent and discriminant validity. The Polish version of the QLQ-LMC21 proved to be a valid and reliable questionnaire.