Risk factors for lymph node metastases of facial cutaneous squamous cell carcinoma. Issue 8 (August 2017)

• Record Type: Journal Article
• Authors: Obermeier, Katharina; Tröltzsch, Matthias; Ehrenfeld, Michael; Smolka, Wenko
• Is Part Of: Journal of cranio-maxillofacial surgery. Volume 45:Issue 8(2017)
• Page Start: 1138
• Page End: 1142
• Publication Date: 2017-08
• Subjects: Cutaneous squamous cell carcinoma -- Lymph node metastases -- Risk factors; Skull -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Surgery, Plastic -- Periodicals; Maxilla -- surgery -- Periodicals; Face -- surgery -- Periodicals; Skull -- surgery -- Periodicals; Oral Surgical Procedures -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Surgery, Plastic -- Periodicals; Surgery, Oral -- Periodicals; Electronic journals; 617.514
• DOI: 10.1016/j.jcms.2017.05.015
• Languages: English
• ISSNs: 1010-5182

Abstract

Abstract: Purpose: Determining the risk factors for lymph node metastases of facial cutaneous squamous cell carcinoma and identifying their value for predicting nodal spread. Material and methods: Data on 99 patients were examined retrospectively. Conditions such as tumor staging, tumor thickness, location, histological grading, R1-resection, local recurrence, lymph node metastases, and neurovascular and lymphovascular invasion were evaluated. Statistical analysis was performed using a logistic regression analysis and Fisher's test. Results: Logistic regression analysis indicates that poor differentiation, R1-resection, and periorbital location are high risk factors for nodal spread in facial cutaneous squamous cell carcinoma. Conclusion: Patients who show poorly differentiated facial cutaneous squamous cell carcinoma and/or have had previous R1-resection might benefit from treatment of regional lymph nodes.