Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase. Issue 5 (21st March 2016)

• Record Type: Journal Article
• Authors: Muroi, Makoto; Futamura, Yushi; Osada, Hiroyuki
• Is Part Of: Natural product reports. Volume 33:Issue 5(2016:May)
• Page Start: 621
• Page End: 625
• Publication Date: 2016-03-21
• Subjects: Natural products -- Periodicals; Produits naturels -- Périodiques; 547.7
• DOI: 10.1039/c5np00106d
• Languages: English
• ISSNs: 0265-0568

Abstract

Abstract : Target identification of new bioactive compounds has been achieved by both our direct and indirect approaches. Here, we highlight the utility of the latter approaches, MorphoBase and ChemProteoBase. Abstract : Covering: up to the end of 2015. Many useful compounds from natural products have been discovered through phenotype-based screening. However, the target identification process for compounds is laborious and time-consuming. With the development of new equipment and methodologies for biological analyses, a variety of profiling methods that utilize large sets of experimental data have been established. Here, we highlight the utility of our identification approaches, MorphoBase and ChemProteoBase.