Unprecedented staining of polar lipids by a luminescent rhenium complex revealed by FTIR microspectroscopy in adipocytes. Issue 7 (12th May 2016)

• Record Type: Journal Article
• Authors: Bader, C. A.; Carter, E. A.; Safitri, A.; Simpson, P. V.; Wright, P.; Stagni, S.; Massi, M.; Lay, P. A.; Brooks, D. A.; Plush, S. E.
• Is Part Of: Molecular bioSystems. Volume 12:Issue 7(2016:Jul.)
• Page Start: 2064
• Page End: 2068
• Publication Date: 2016-05-12
• Subjects: Molecular biology -- Periodicals; Biochemistry -- Periodicals; 571.7405
• DOI: 10.1039/c6mb00242k
• Languages: English
• ISSNs: 1742-206X

Abstract

Abstract : Localisation of a neutral rhenium(i ) tricarbonyl phenanthroline species to regions of high polar lipid concentrations is demonstrated by Fourier transform infrared (FTIR) microspectroscopy. Abstract : Fourier transform infrared (FTIR) microspectroscopy and confocal imaging have been used to demonstrate that the neutral rhenium(i ) tricarbonyl 1, 10-phenanthroline complex bound to 4-cyanophenyltetrazolate as the ancillary ligand is able to localise in regions with high concentrations of polar lipids such as phosphatidylethanolamine (PE), sphingomyelin, sphingosphine and lysophosphatidic acid (LPA) in mammalian adipocytes.