Introduction to the 2nd Meeting on Immunity and Inflammation in Epilepsy (IIE2016). (July 2017)

• Record Type: Journal Article
• Authors: Vezzani, Annamaria; Rüegg, Stephan
• Other Names: Vezzani Annamaria guestEditor.; Rüegg Stephan guestEditor.
• Is Part Of: Epilepsia. Volume 58(2017)Supplement 3
• Page Start: 7
• Page End: 10
• Publication Date: 2017-07
• Subjects: Inflammation -- Immunity -- Epilepsy -- Anti‐inflammatory drugs -- Disease modification -- Epileptogenesis -- Biomarker; Epilepsy -- Periodicals; 616.853
• DOI: 10.1111/epi.13780
• Languages: English
• ISSNs: 0013-9580

Abstract

Summary: We report about the main topics presented during this meeting which was devoted to discuss the new emerging evidence for a role of immune‐ and inflammation‐related mechanisms in various autoimmune and nonautoimmune forms of epilepsy. Major emphasis was given to novel immune/inflammatory mechanisms contributing to seizures and neurological comorbidities as well as to the discovery and validation of noninvasive biomarkers of brain inflammation which may be used to monitor epileptogenesis and predict the therapeutic effects of treatments. The key question was whether our scientific community is ready for the translation of the results of laboratory research to clinical studies, and how to best design clinical trials of anti‐inflammatory drugs with potential disease‐modifying effects.