Catch Shiny Droplets in Suspension—Finding the Needle in a Haystack. Issue 7 (20th July 2017)

• Record Type: Journal Article
• Authors: Hein-Fuchs, Nina V.; König, Renate
• Is Part Of: Cell chemical biology. Volume 24:Issue 7(2017)
• Page Start: 783
• Page End: 784
• Publication Date: 2017-07-20
• Subjects: Biochemistry -- Periodicals; 572.05
• DOI: 10.1016/j.chembiol.2017.07.004
• Languages: English
• ISSNs: 2451-9456

Abstract

Abstract : In a recent issue of Cell Chemical Biology, Chaipan et al. (2017) described a high-throughput screening methodology to identify epitopes on HIV-1 particles recognized by broadly neutralizing antibodies. The approach utilizes a droplet-based microfluidics platform combining robust phenotypic single-virus sorting with next-generation sequencing of viral quasispecies. Abstract : In a recent issue of Cell Chemical Biology, Chaipan et al. (2017) described a high-throughput screening methodology to identify epitopes on HIV-1 particles recognized by broadly neutralizing antibodies. The approach utilizes a droplet-based microfluidics platform combining robust phenotypic single-virus sorting with next-generation sequencing of viral quasispecies.