Successful treatment with placenta‐derived decidual stromal cells in a pediatric patient with life‐threatening acute gastrointestinal graft‐versus‐host disease. (13th June 2017)

• Record Type: Journal Article
• Authors: Gustafsson, Britt; Frisk, Per; Szakos, Attilla; Sadeghi, Behnam; Ringdén, Olle; Frost, Britt‐Marie
• Is Part Of: Pediatric transplantation. Volume 21:Number 5(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-06-13
• Subjects: acute graft‐versus‐host disease -- decidual stromal cells -- pediatric allogeneic hematopoietic stem cell transplantation -- steroid‐refractory gastrointestinal bleedings; Transplantation of organs, tissues, etc. in children -- Periodicals; 617.95408305
• DOI: 10.1111/petr.12990
• Languages: English
• ISSNs: 1397-3142

Abstract

Abstract: Severe aGvHD is a life‐threatening complication after allogeneic HSCT. The GI tract is considered to play a key role in aGvHD, where the disease process can start and is one of the major target organs. Here, we present a case of a one‐year‐old child with a life‐threatening GI‐aGvHD stage IV, post‐HSCT, resistant to steroids and MMF for 4 weeks. He was successfully treated with placenta‐derived DSC.