Self‐gated 4D multiphase, steady‐state imaging with contrast enhancement (MUSIC) using rotating cartesian K‐space (ROCK): Validation in children with congenital heart disease. Issue 2 (16th August 2016)

• Record Type: Journal Article
• Authors: Han, Fei; Zhou, Ziwu; Han, Eric; Gao, Yu; Nguyen, Kim‐Lien; Finn, J. Paul; Hu, Peng
• Is Part Of: Magnetic resonance in medicine. Volume 78:Issue 2(2017)
• Page Start: 472
• Page End: 483
• Publication Date: 2016-08-16
• Subjects: MR angiography -- cardiac CINE -- self‐gating -- pediatric congenital heart disease -- motion compensation; Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.26376
• Languages: English
• ISSNs: 0740-3194

Abstract

Abstract : Purpose: To develop and validate a cardiac‐respiratory self‐gating strategy for the recently proposed multiphase steady‐state imaging with contrast enhancement (MUSIC) technique. Methods: The proposed SG strategy uses the ROtating Cartesian K‐space (ROCK) sampling, which allows for retrospective k‐space binning based on motion surrogates derived from k‐space center line. The k‐space bins are reconstructed using a compressed sensing algorithm. Ten pediatric patients underwent cardiac MRI for clinical reasons. The original MUSIC and 2D‐CINE images were acquired as a part of the clinical protocol, followed by the ROCK‐MUSIC acquisition, all under steady‐state intravascular distribution of ferumoxytol. Subjective scores and image sharpness were used to compare the images of ROCK‐MUSIC and original MUSIC. Results: All scans were completed successfully without complications. The ROCK‐MUSIC acquisition took 5 ± 1 min, compared to 8 ± 2 min for the original MUSIC. Image scores of ROCK‐MUSIC were significantly better than original MUSIC at the ventricular outflow tracts (3.9 ± 0.3 vs. 3.3 ± 0.6, P < 0.05). There was a strong trend toward superior image scores for ROCK‐MUSIC in the other anatomic locations. Conclusion: ROCK‐MUSIC provided images of equal or superior image quality compared to original MUSIC, and this was achievable with 40% savings in scan time and without the need for physiologic signal. Magn Reson Med 78:472–483, 2017. © 2016 International Society for Magnetic Resonance in Medicine