Nickel‐Catalyzed Desulfitative Suzuki–Miyaura Cross‐Coupling of N, N‐Disulfonylmethylamines and Arylboronic Acids. Issue 29 (9th September 2014)

• Record Type: Journal Article
• Authors: Chen, Liangshun; Lang, Hongyue; Fang, Lei; Yu, Jianjun; Wang, Limin
• Is Part Of: European journal of organic chemistry. Issue 29(2014)
• Page Start: 6385
• Page End: 6389
• Publication Date: 2014-09-09
• Subjects: Synthetic methods -- C–C cou­pling -- Cross‐coupling -- Biaryls -- Nickel; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201402919
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: A nickel‐catalyzed approach for the synthesis of biaryl compounds from N, N ‐disulfonylmethylamines and arylboronic acids has been developed. Instead of arenesulfonyl chlorides, various N, N ‐disulfonylmethylamines were used as the aryl source through extrusion of SO2 to give cross‐coupling products in moderate to good yields. Abstract : A NiCl2 (dppp)‐catalyzed [dppp = 1, 3‐bis(diphenylphosphino)propane] desulfitative Suzuki–Miyaura cross‐coupling reaction between N, N ‐disulfonylmethylamines and arylboronic acids is described for the first time. The biaryl compounds are obtained in moderate to good yields.