Rapid Prototyping of a Low-cost Graphene-based Impedimetric Biosensor. (2017)

• Record Type: Journal Article
• Authors: Popescu, Sinziana; Dale, Carl; Keegan, Neil; Ghosh, Biswajit; Kaner, Richard; Hedley, John
• Is Part Of: Procedia technology. Volume 27(2016)
• Page Start: 274
• Page End: 276
• Publication Date: 2017
• Subjects: graphene -- reduced graphene oxide -- impedimetric biosensor -- interdigitated electrode array -- electroless nickel deposition; Technology -- Congresses; Technology -- Periodicals; Engineering -- Congresses; Engineering -- Periodicals; Engineering; Technology; Conference proceedings; Periodicals; 605
• DOI: 10.1016/j.protcy.2017.04.116
• Languages: English
• ISSNs: 2212-0173

Abstract

Abstract: This paper presents a preliminary investigation towards rapid prototyping of a low-cost biosensor based on reduced graphene oxide (rGO). The devices are fabricated via a laser scribing process and their functionality is demonstrated by their functionalization and subsequent immobilization of 7% bovine serum albumin (BSA). Non-faradaic electrochemical impedance spectroscopy (EIS) indicated a 33-42% decrease in impedance upon immobilization. An electroless nickel deposition process is demonstrated to enable electrical contacts to the device, with optimized plating conditions (pH, temperature) leading to a rGO-nickel contact resistance of 19 Ω/mm 2 .