A Novel Sandwich-type Electrochemical Aptasensor Based on GR-3D Au and Aptamer-AuNPs-HRP for Sensitive Detection of Oxytetracycline. (2017)

• Record Type: Journal Article
• Authors: Liu, Su; Wang, Yu; Xu, Wei; Leng, Xueqi; Wang, Hongzhi; Guo, Yuna; Huang, Jiadong
• Is Part Of: Procedia technology. Volume 27(2016)
• Page Start: 151
• Page End: 152
• Publication Date: 2017
• Subjects: Graphene-gold nanostructure -- Horseradish peroxidase -- Electrochemical aptasensor -- Sandwich-type -- Oxytetracycline; Technology -- Congresses; Technology -- Periodicals; Engineering -- Congresses; Engineering -- Periodicals; Engineering; Technology; Conference proceedings; Periodicals; 605
• DOI: 10.1016/j.protcy.2017.04.066
• Languages: English
• ISSNs: 2212-0173

Abstract

Abstract: A novel sandwich-type electrochemical aptasensor has been fabricated and applied for sensitive and selective detection of antibiotic oxytetracycline (OTC). This sensor was based on graphene-three dimensional nanostructure gold nanocomposite (GR-3D Au) and aptamer-AuNPs-horseradish peroxidase (HRP) nanoprobes as signal amplification. The aptamer and HRP modified Au nanoparticles provide high affinity and ultrasensitive electrochemical probe with excellent specificity for OTC.