LSPR Biosensor Based on Nanostructured Gold Films: Detection of Mycotoxins. (2017)

• Record Type: Journal Article
• Authors: Al-Rubaye, Ali Ghamin; Nabok, Alexei; Tsargorodska, Anna
• Is Part Of: Procedia technology. Volume 27(2016)
• Page Start: 131
• Page End: 132
• Publication Date: 2017
• Subjects: LSPR -- gold nano-structures -- spectroscopic ellipsometry -- TIRE -- immunosensing -- mycotoxins; Technology -- Congresses; Technology -- Periodicals; Engineering -- Congresses; Engineering -- Periodicals; Engineering; Technology; Conference proceedings; Periodicals; 605
• DOI: 10.1016/j.protcy.2017.04.057
• Languages: English
• ISSNs: 2212-0173

Abstract

Abstract: This work focuses on the development of optical sensors based on the LSPR phenomenon in nano-structured gold films suitable for detection of mycotoxins. A simple technology of annealing thin gold films was utilized for the formation of gold nano-islands exhibiting the LSPR effect. The morphology of gold nano-structures produced was studied with SEM and AFM while their optical properties were analysed with UV-vis absorption spectroscopy and spectroscopic ellipsometry (SE). A blue spectral shift of LSPR band caused by changes in the refractive index of medium constitutes the main principle of LSPR sensing. Bio-sensing tests were attempted using SE in total internal reflection mode (TIRE); a noticeable spectral shift was recorded on course of immune binding of aflatoxin B1 to specific antibodies immobilized on the surface of gold.