Nanostructured Platform Based on Graphene-polypyrrole Composite for Immunosensor Fabrication. (2017)

• Record Type: Journal Article
• Authors: Cernat, Andreea; Tertiș, Mihaela; Păpară, Claudia Nicoleta; Bodoki, Ede; Săndulescu, Robert
• Is Part Of: Procedia technology. Volume 27(2016)
• Page Start: 108
• Page End: 109
• Publication Date: 2017
• Subjects: graphene -- polypyrrole -- immunosensor -- acetaminophen -- nanosphere lithography; Technology -- Congresses; Technology -- Periodicals; Engineering -- Congresses; Engineering -- Periodicals; Engineering; Technology; Conference proceedings; Periodicals; 605
• DOI: 10.1016/j.protcy.2017.04.047
• Languages: English
• ISSNs: 2212-0173

Abstract

Abstract: A hybrid graphene-polypyrrole (PPy) composite-based platform was elaborated by using nanosphere lithography structuration. This platform was further used for the antibody anti-acetaminophen immobilization in order to obtain an immunosensor for selective detection of paracetamol (acetaminophen) by using electrochemical methods. After patterning of the composite layer, the five-fold improvement of electrochemical signal was observed, suggesting that a higher amount of antibody was immobilized. This strategy permitted the ease and controlled immobilization of bioreceptors on the composite graphene-PPy platform and enhanced the sensitivity for paracetamol detection.