Breastfeeding and the Risk of Maternal Cardiovascular Disease: A Prospective Study of 300 000 Chinese Women. Issue 6 (June 2017)

• Record Type: Journal Article
• Authors: Peters, Sanne A. E.; Yang, Ling; Guo, Yu; Chen, Yiping; Bian, Zheng; Du, Jianwei; Yang, Jie; Li, Shanpeng; Li, Liming; Woodward, Mark; Chen, Zhengming
• Other Names: Chen Junshi investigator.; Collins Rory investigator.; Peto Richard investigator.; Bennett Derrick investigator.; Chang Yumei investigator.; Clarke Robert investigator.; Du Huaidong investigator.; Fan Xuejuan investigator.; Gilbert Simon investigator.; Hacker Alex investigator.; Holmes Michael investigator.; Iona Andri investigator.; Kartsonaki Christiana investigator.; Kerosi Rene investigator.; Kong Ling investigator.; Kurmi Om investigator.; Lancaster Garry investigator.; Lewington Sarah investigator.; McDonnell John investigator.; Millwood Iona investigator.; Nie Qunhua investigator.; Radhakrishnan Jayakrishnan investigator.; Rafiq Sajjad investigator.; Ryder Paul investigator.; Sansome Sam investigator.; Schmidt Dan investigator.; Sherliker Paul investigator.; Sohoni Rajani investigator.; Turnbull Iain investigator.; Walters Robin investigator.; Wang Jenny investigator.; Wang Lin investigator.; Yang Xiaoming investigator.; Chen Ge investigator.; Han Bingyang investigator.; Hou Can investigator.; Lv Jun investigator.; Pei Pei investigator.; Qu Shuzhen investigator.; Tan Yunlong investigator.; Yu Canqing investigator.; Zhou Huiyan investigator.; Pang Zengchang investigator.; Gao Ruqin investigator.; Wang Shaojie investigator.; Liu Yongmei investigator.; Du Ranran investigator.; Zang Yajing investigator.; Cheng Liang investigator.; Tian Xiaocao investigator.; Zhang Hua investigator.; Lv Silu investigator.; Wang Junzheng investigator.; Hou Wei investigator.; Yin Jiyuan investigator.; Jiang Ge investigator.; Liu Shumei investigator.; Pang Zhigang investigator.; Zhou Xue investigator.; Yang Liqiu investigator.; He Hui investigator.; Yu Bo investigator.; Li Yanjie investigator.; Mu Huaiyi investigator.; Xu Qinai investigator.; Dou Meiling investigator.; Ren Jiaojiao investigator.; Wang Shanqing investigator.; Hu Ximin investigator.; Wang Hongmei investigator.; Chen Jinyan investigator.; Fu Yan investigator.; Fu Zhenwang investigator.; Wang Xiaohuan investigator.; Dong Hua investigator.; Weng Min investigator.; Zheng Xiangyang investigator.; Li Yijun investigator.; Li Huimei investigator.; Li Chenglong investigator.; Wu Ming investigator.; Zhou Jinyi investigator.; Tao Ran investigator.; Shen Jie investigator.; Hu Yihe investigator.; Lu Yan investigator.; Gao Yan investigator.; Ma Liangcai investigator.; Zhou Renxian investigator.; Tang Aiyu investigator.; Zhang Shuo investigator.; Jin Jianrong investigator.; Tang Zhenzhu investigator.; Chen Naying investigator.; Huang Ying investigator.; Li Mingqiang investigator.; Meng Jinhuai investigator.; Pan Rong investigator.; Jiang Qilian investigator.; Qing Jingxin investigator.; Zhang Weiyuan investigator.; Liu Yun investigator.; Wei Liuping investigator.; Zhou Liyuan investigator.; Chen Ningyu investigator.; Yang Jun investigator.; Guan Hairong investigator.; Wu Xianping investigator.; Zhang Ningmei investigator.; Chen Xiaofang investigator.; Tang Xuefeng investigator.; Luo Guojin investigator.; Li Jianguo investigator.; Chen Xiaofang investigator.; Wang Jian investigator.; Liu Jiaqiu investigator.; Sun Qiang investigator.; Ge Pengfei investigator.; Ren Xiaolan investigator.; Dong Caixia investigator.; Zhang Hui investigator.; Mao Enke investigator.; Wang Xiaoping investigator.; Wang Tao investigator.; Liu Guohua investigator.; Zhu Baoyu investigator.; Zhou Gang investigator.; Feng Shixian investigator.; Chang Liang investigator.; Fan Lei investigator.; Gao Yulian investigator.; He Tianyou investigator.; Jiang Li investigator.; Sun Huarong investigator.; He Pan investigator.; Hu Chen investigator.; Lv Qiannan investigator.; Zhang Xukui investigator.; Yu Min investigator.; Hu Ruying investigator.; Fang Le investigator.; Wang Hao investigator.; Qian Yijian investigator.; Wang Chunmei investigator.; Xie Kaixue investigator.; Chen Lingli investigator.; Pan Yaxing investigator.; Pan Dongxia investigator.; Huang Yuelong investigator.; Chen Biyun investigator.; Jin Donghui investigator.; Liu Huilin investigator.; Fu Zhongxi investigator.; Xu Qiaohua investigator.; Xu Xin investigator.; g Youping investigator.; Jia Weifang investigator.; Li Xianzhi investigator.; Zhang Libo investigator.; Qiu Zhe investigator.;
• Is Part Of: Journal of the American Heart Association. Volume 6:Issue 6(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-06
• Subjects: breastfeeding -- cardiovascular disease -- China -- epidemiology -- risk factor -- women; Heart -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; Cerebrovascular disease -- Periodicals; Cardiology -- Periodicals; 616.1
• DOI: 10.1161/JAHA.117.006081
• Languages: English
• ISSNs: 2047-9980

Abstract

Abstract : Background: Breastfeeding confers substantial benefits to child health and has also been associated with lower risk of maternal cardiovascular diseases (CVDs) in later life. However, the evidence on the effects of CVD is still inconsistent, especially in East Asians, in whom the frequency and duration of breastfeeding significantly differ from those in the West. Methods and Results: In 2004–2008, the nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30 to 79 years from 10 diverse regions across China. During 8 years of follow‐up, 16 671 incident cases of coronary heart disease and 23 983 cases of stroke were recorded among 289 573 women without prior CVD at baseline. Cox regression yielded adjusted hazard ratios (HRs) and 95% CIs for incident CVD by breastfeeding. Overall, ≈99% of women had given birth, among whom 97% reported a history of breastfeeding, with a median duration of 12 months per child. Compared with parous women who had never breastfed, ever breastfeeding was associated with a significantly lower risk of CVD, with adjusted HRs of 0.91 (95% CI, 0.84–0.99) for coronary heart disease and 0.92 (95% CI, 0.85–0.99) for stroke. Women who had breastfed for ≥24 months had an 18% (HR, 0.82; 0.77–0.87) lower risk of coronary heart disease and a 17% (HR, 0.83; 0.79–0.87) lower risk of stroke compared with women who had never breastfed. Among women who ever breastfed, each additional 6 months of breastfeeding per child was associated with an adjusted HR of 0.96 (95% CI, 0.94–0.98) for coronary heart disease and 0.97 (95% CI, 0.96–0.98) for stroke. Conclusions: Among Chinese women, a history of breastfeeding was associated with an ≈10% lower risk of CVD in later life and the magnitude of the inverse association was stronger among those with a longer duration of breastfeeding.