Aldehydes as Carbon Radical Acceptors: Silver Nitrate Catalyzed Cascade Decarboxylation and Oxidative Cyclization toward Dihydroflavonoid Derivatives. Issue 14 (8th May 2017)

• Record Type: Journal Article
• Authors: Yang, Wen‐Chao; Dai, Peng; Luo, Kai; Ji, Yi‐Gang; Wu, Lei
• Is Part Of: Advanced synthesis & catalysis. Volume 359:Issue 14(2017)
• Page Start: 2390
• Page End: 2395
• Publication Date: 2017-05-08
• Subjects: Ketones -- Decarboxylation -- Aldehydic C−H bonds -- Oxidative cyclization -- Diacylation; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201601407
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Silver nitrate‐catalyzed cascade decarboxylation and oxidative cyclization of α ‐oxocarboxylic acids, alkenes, and aldehydes is demonstrated for the first time. With ammonium persulfate as the oxidant, the cascade reactions afford dihydroflavonoid derivatives as products in moderate to good yields, exhibiting a broad substrate tolerance. Control experiments indicated that the mechanism includes a radical pathway with aldehydes as the carbon radical acceptors. Abstract :