Cerium(III)-catalyzed C3-acylation of indoles with nitroolefins. Issue 7 (17th February 2016)

• Record Type: Journal Article
• Authors: Feng, Cheng-Tao; Zhu, Hui-Zhi; Li, Zhong; Luo, Zaigang; Wu, Song-Song; Ma, Shi-Tang
• Is Part Of: Tetrahedron letters. Volume 57:Issue 7(2016)
• Page Start: 800
• Page End: 803
• Publication Date: 2016-02-17
• Subjects: Indoles -- Nitroolefins -- Acylation reaction -- Ketone; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2016.01.029
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: A novel and efficient cerium(III)-catalyzed C3-selective acylation of N–H indoles using nitroolefins as acylating reagents was first developed. It was found that the use of CeCl3 as a catalyst achieves an unexpected and highly efficient C–C bond cleavage.