Self-assembly of bioactive peptides, peptide conjugates, and peptide mimetic materials. Issue 28 (29th June 2017)

• Record Type: Journal Article
• Authors: Edwards-Gayle, Charlotte J. C.; Hamley, Ian W.
• Is Part Of: Organic & biomolecular chemistry. Volume 15:Issue 28(2017)
• Page Start: 5867
• Page End: 5876
• Publication Date: 2017-06-29
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob01092c
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : Self-assembling peptide and peptide conjugates have attracted great attention due to their biocompatibility, biodegradability and biofunctionality. This review covers self-assembly of amphiphilic peptides and peptide mimetic materials, as well as their potential applications. Abstract : Molecular self-assembly is a multi-disciplinary field of research, with potential chemical and biological applications. One of the main driving forces of self-assembly is molecular amphiphilicity, which can drive formation of complex and stable nanostructures. Self-assembling peptide and peptide conjugates have attracted great attention due to their biocompatibility, biodegradability and biofunctionality. Understanding assembly enables the better design of peptide amphiphiles which may form useful and functional nanostructures. This review covers self-assembly of amphiphilic peptides and peptide mimetic materials, as well as their potential applications.