Chemoenzymatic synthesis of a peptide containing nylon monomer units for thermally processable peptide material application. Issue 29 (31st May 2017)

• Record Type: Journal Article
• Authors: Yazawa, Kenjiro; Gimenez-Dejoz, Joan; Masunaga, Hiroyasu; Hikima, Takaaki; Numata, Keiji
• Is Part Of: Polymer chemistry. Volume 8:Issue 29(2017)
• Page Start: 4172
• Page End: 4176
• Publication Date: 2017-05-31
• Subjects: Polymers -- Periodicals; Macromolecules -- Periodicals; Polymerization -- Periodicals; 547.705
• DOI: 10.1039/c7py00770a
• Languages: English
• ISSNs: 1759-9954

Abstract

Abstract : Chemoenzymatic polymerization by papain produced the copolymer ofl -leucine and nylon monomers, which showed melting behavior at around 200 °C. Abstract : Peptides exhibit no melting behavior during heating due to their strong intermolecular hydrogen bonds, which limits the use of peptides as a bulk material. Here, we added a melting point to peptides by introducing nylon monomer units via papain-catalyzed chemoenzymatic synthesis. The peptides containing 14 mol% nylon units had a melting point of approximately 200 °C.