Schiff base derived Fe3+-selective fluorescence turn-off chemsensors based on triphenylamine and indole: synthesis, properties and application in living cells. Issue 57 (19th July 2017)

• Record Type: Journal Article
• Authors: Pan, Chengqiang; Wang, Kai; Ji, Shaomin; Wang, Huaqian; Li, Zongzhi; He, Huahong; Huo, Yanping
• Is Part Of: RSC advances. Volume 7:Issue 57(2017)
• Page Start: 36007
• Page End: 36014
• Publication Date: 2017-07-19
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra05064j
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A Schiff base with an AIE effect could act as a turn-off fluorescent chemosensor for Fe 3+ in living cells. Abstract : Two Schiff base derivatives (S1 andS2 ) containing triphenylamine and indole fluorophores groups have been synthesized via a one-pot reaction and utilized as fluorescence turn-off sensors towards Fe 3+ ions in THF.S1 andS2 demonstrated fluorescence turn-off sensing towards Fe 3+ ions, via photoinduced electron transfer (PET). The 2 : 1 stoichiometries of the sensor complexes ([S1, S2 ] + Fe 3+ ) were calculated from Job plots based on UV-vis absorption titrations. The detection limits (LODs) of [S1, S2 ] + Fe 3+ sensor responses were calculated by their standard deviation, linear fitting and from their fluorescence binding isotherms. More importantly, [S1, S2 ] + Fe 3+ sensors were found to be active in aqueous media within a wide range of pH values. In addition, biological imaging and membrane permeability demonstrated thatS1 could act as a turn-off fluorescence chemosensor for Fe 3+ in living cells.