Assessment of Short‐term Blood Pressure Variability in Patients With Ascending Aortic Dilatation. Issue 12 (30th November 2015)

• Record Type: Journal Article
• Authors: Karataş, Mehmet Baran; İpek, Göktürk; Çanga, Yiğit; Güngör, Barış; Özcan, Kazim Serhan; Arugaslan, Emre; Günaydin, Zeki Yüksel; Durmuş, Gündüz; Onuk, Tolga; Kalenderoğlu, Koray; Akdeniz, Evliya; Bolca, Osman
• Is Part Of: Clinical cardiology. Volume 38:Issue 12(2015:Dec.)
• Page Start: 757
• Page End: 762
• Publication Date: 2015-11-30
• Subjects: Cardiology -- Periodicals; 616.12005
• DOI: 10.1002/clc.22485
• Languages: English
• ISSNs: 0160-9289

Abstract

ABSTRACT: Background: Blood pressure variability (BPV) is a novel parameter related to adverse cardiovascular findings and events, especially in hypertensive patients. The aim of the present study was to investigate the relationship between short‐term BPV and ascending aortic dilatation (AAD). Hypothesis: Hypertensive patients with AAD may exhibit higher short‐term BPV compared to hypertensive patients with normal diameter ascending aorta and BPV may be correlated with aortic sizes. Methods: Seventy‐six hypertensive patients with AAD and 181 hypertensive patients with a normal‐diameter ascending aorta were retrospectively enrolled in the study. Clinical data, echocardiographic characteristics, and 24‐hour ambulatory blood pressure monitoring characteristics were compared between the 2 groups. Standard deviation (SD) and Δ of BP were used as parameters of BPV. Results: Although 24‐hour mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were similar between the 2 groups, the SD of SBP and SD of DBP values were significantly higher in AAD patients (17.2 ± 6.8 vs 13.8 ± 3.5, P < 0.01; and 12.1 ± 5.1 vs 10.7 ± 3.1, P = 0.02, respectively). Daytime SD of SBP values were higher in AAD patients, whereas nighttime SD of SBP values did not differ between groups. In multivariate linear regression analysis, 24‐hour SD of SBP, 24‐hour Δ SBP, daytime SD of SBP, daytime Δ SBP, and left ventricular mass index were independently correlated with aortic size index. Conclusions: Our study revealed higher levels of short‐term BPV in hypertensive patients with AAD. This conclusion warrants further study.