Occurrence of hemotropic mycoplasmas in non-human primates (Alouatta caraya, Sapajus nigritus and Callithrix jacchus) of southern Brazil. (June 2017)

• Record Type: Journal Article
• Authors: Cubilla, Michelle P.; Santos, Leonilda C.; de Moraes, Wanderlei; Cubas, Zalmir S.; Leutenegger, Christian M.; Estrada, Marko; Vieira, Rafael F.C.; Soares, Maurilio J.; Lindsay, LeAnn L.; Sykes, Jane E.; Biondo, Alexander W.
• Is Part Of: Comparative immunology, microbiology and infectious diseases. Volume 52(2017)
• Page Start: 6
• Page End: 13
• Publication Date: 2017-06
• Subjects: Hemoplasma -- Vector-borne disease -- Wild mammal -- Monkey; Communicable diseases in animals -- Periodicals; Veterinary immunology -- Periodicals; Veterinary microbiology -- Periodicals; Immunology -- Periodicals; Microbiology -- Periodicals; Communicable diseases -- Periodicals; Communicable Diseases -- immunology -- Periodicals; Communicable Diseases -- veterinary -- Periodicals; Allergy and Immunology -- Periodicals; Microbiology -- Periodicals; Veterinary Medicine -- Periodicals; Immunologie -- Périodiques; Microbiologie -- Périodiques; Maladies infectieuses -- Périodiques; Communicable diseases; Immunology; Microbiology; Electronic journals; Periodicals; 636.08969
• DOI: 10.1016/j.cimid.2017.05.002
• Languages: English
• ISSNs: 0147-9571

Abstract

Highlights: Hemoplasmas may infect Alouatta caraya and Sapajus nigritus monkeys. Callithrix jacchus was not infected, as in previous study. Infection appeared to be associated with male sex and free-ranging habitat. Hemoplasmas infection was not associated with anemia. The effects of hemoplasma chronic infection in monkeys remain unclear. Abstract: Hemoplasmas, the erythrocyte-associated mycoplasmas, have been detected in several primates, causing mostly subclinical infection. This study aimed to determine the prevalence of hemoplasma infection in captive and free-ranging monkeys from southern Brazil, as well as factors and hematological abnormalities associated with infection. Blood samples from 40 non-human primates (NHP) were tested for hemoplasmas and coinfections. An overall of 10/40 (25.0%) NHP tested positive for hemoplasmas using PCR-based assays, including 9/14 (64.3%) black howler monkeys ( Alouatta caraya ) and 1/24 (4.2%) black-horned capuchin ( Sapajus nigritus ). Infection was not statistically associated with anemia, but wild-born monkeys and male black howler monkeys were more likely to be positive when compared with captive-born animals and female black howler monkeys, respectively. The sequences from the black howler monkey hemoplasma were similar (94% identity) to the squirrel monkey hemoplasma (" Candidatus Mycoplasma kahanei") and were phylogenetically located in a different cluster when compared to the human hemoplasma (" Candidatus Mycoplasma haemohominis").