TDS exposure project: How and when to consider seasonalityin a total diet study?. (July 2017)

• Record Type: Journal Article
• Authors: Fabrice Elegbede, Chabi; Papadopoulos, Alexandra; Kolbaum, Anna Elena; Turrini, Aida; Mistura, Lorenza; Lindtner, Oliver; Sirot, Véronique
• Is Part Of: Food and chemical toxicology. Volume 105(2017)
• Page Start: 119
• Page End: 126
• Publication Date: 2017-07
• Subjects: Total diet study -- Seasonality -- Exposure assessment -- Trace elements -- Persistent organic pollutants -- Mycotoxins; DL-PCB dioxin-like polychlorinated biphenyl -- DON deoxinivalenol -- EFSA European Food Safety Authority -- INCA2 second French Individual and National Food Consumption Survey -- IQR interquartile range -- JECFA Joint FAO/WHO Expert Committee on Food Additives -- LB lower bound approach -- LOD limit of detection -- LOQ limit of quantification -- NDL-PCB non dioxin-like polychlorinated biphenyl -- OTA ochratoxin A -- PAH polycyclic aromatic compound -- PBDE polybromodiphenylether -- PCB polychlorinated biphenyl -- PCDD/F dioxins and furans -- PFAA perfluoroalkyl acid -- PTWI provisional tolerable weekly intake -- TDI tolerable daily intake -- TDS total diet study -- UB upper bound approach; Toxicology -- Periodicals; Food poisoning -- Periodicals; Food Poisoning -- Periodicals; Toxicology -- Periodicals; Toxicologie -- Périodiques; Intoxications alimentaires -- Périodiques; Food poisoning; Toxicology; Periodicals; Electronic journals; 615.9
• DOI: 10.1016/j.fct.2017.03.045
• Languages: English
• ISSNs: 0278-6915

Abstract

Abstract: Seasonality is a key issue of total diet studies (TDS), as season may impact consumption patterns and concentrations of food chemicals, then exposure levels. This work aimed at analyzing the impact on dietary exposure of different options of seasonality management, to propose guidelines for TDS sampling. Dietary exposure to nine chemicals was assessed for adults and children from the second French Individual and National Food Consumption Survey: arsenic, copper, manganese, dioxins, furans, dioxin-like and non dioxin-like PCBs, deoxinivalenol and ochratoxin A. Seasonality was considered either in both consumption and concentration data, consumption data only, or concentration data only. Results showed significant differences between exposures during different seasons. For most chemicals, the difference between seasonal exposures may not be mainly driven by seasonality of consumption, but partly by seasonality of concentration. Results on risk assessment remained generally the same. If the main objective of the TDS is the risk assessment, considering season for sampling could be costly but with a low added value in terms of results. For exposure refinement, season has to be considered in the sampling design. More particularly, seasonal samples should be kept separately for chemicals with expected seasonal variation in concentrations, such as some metals or mycotoxins. Highlights: Seasonality is a key issue of total diet studies (TDS). Seasonality management options have been tested for a TDS sampling and exposure assessment. The differences between seasonal exposures may not be mainly driven by seasonality of consumption. The differences between seasonal exposures may be mainly driven by seasonality of concentration. Seasonality in a TDS sampling plan has to be considered according to the objective and to the chemical studied.