Vanadium(V)‐Induced Oxidative Cross‐Coupling of Various Boron and Silyl Enolates. Issue 12 (1st June 2017)

• Record Type: Journal Article
• Authors: Amaya, Toru; Osafune, Yuma; Maegawa, Yusuke; Hirao, Toshikazu
• Is Part Of: Chemistry, an Asian journal. Volume 12:Issue 12(2017)
• Page Start: 1301
• Page End: 1304
• Publication Date: 2017-06-01
• Subjects: boron enolates -- cross-coupling -- oxidation -- silyl enolates -- vanadium; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.201700470
• Languages: English
• ISSNs: 1861-4728

Abstract

Abstract: Intermolecular oxidative cross‐coupling of two different enolates is one of the most useful reactions to synthesize unsymmetrical 1, 4‐dicarbonyl compounds. In this study, the oxovanadium(V)‐induced intermolecular oxidative cross‐coupling of enolates afforded unsymmetrical 1, 4‐dicarbonyl compounds. Various boron and silyl enolates underwent the formation of ketone–ester, ester–ketone, ester–ester, amide–ketone and amide–ester coupling products . These results clearly show the versatility of the present oxidative cross‐coupling protocol. Abstract : Combining everything : Oxovanadium(V)‐induced intermolecular oxidative cross‐coupling of enolates afforded unsymmetrical 1, 4‐dicarbonyl compounds. Various boron and silyl enolates underwent the formation of ketone–ester, ester–ketone, ester–ester, amide–ketone and amide–ester coupling products.