Determination of Abraham model solute descriptors for 2-methyl-3-nitrobenzoic acid from measured solubility data in alcohol, alkyl ether, alkyl acetate and 2-alkoxyalcohol mono-solvents. (2nd November 2017)

• Record Type: Journal Article
• Authors: Hart, Erin; Ramirez, Ashley M.; Cheeran, Sarah; Barrera, Maribel; Horton, Melissa Y.; Wadawadigi, Anisha; Acree, William E.; Abraham, Michael H.
• Is Part Of: Physics and chemistry of liquids. Volume 55:Number 6(2017)
• Page Start: 796
• Page End: 804
• Publication Date: 2017-11-02
• Subjects: 2-Methyl-3-nitrobenzoic acid solubility -- Abraham model solute descriptors -- alcohol solvents -- alkoxyethanol solvents -- alkyl acetate solvents -- alkyl ether solvents; Liquids -- Periodicals; 530.4205
• DOI: 10.1080/00319104.2017.1283692
• Languages: English
• ISSNs: 0031-9104

Abstract

ABSTRACT: Spectroscopic methods are employed to measure the solubility of 2-methyl-3-nitrobenzoic acid dissolved in 10 alcohol, 3 alkyl ether, 5 alkyl acetate and 3 alkoxyalcohol solvents at 298.2 K. 2-Methyl-3-nitrobenzoic acid is believed to exist in monomeric form in each of the organic solvents studied. The measured solubilities are used to calculate the Abraham model solute descriptors for the monomeric form of 2-methyl-3-nitrobenzoic acid, which will enable one to predict the solubility of 2-methyl-3-nitrobenzoic acid in additional organic solvents. The derived solute descriptors back-calculated the observed solubility data to within 0.06 log units.