Controlled rotation and translation of spherical particles or living cells by surface acoustic waves. Issue 14 (15th June 2017)

• Record Type: Journal Article
• Authors: Bernard, Ianis; Doinikov, Alexander A.; Marmottant, Philippe; Rabaud, David; Poulain, Cédric; Thibault, Pierre
• Is Part Of: Lab on a chip. Volume 17:Issue 14(2017)
• Page Start: 2470
• Page End: 2480
• Publication Date: 2017-06-15
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/c7lc00084g
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : Surface acoustic waves are shown to be powerful tools to control translation and rotation of single particles in microfluidic devices. Abstract : We show experimental evidence of the acoustically-assisted micromanipulation of small objects like solid particles or blood cells, combining rotation and translation, using high frequency surface acoustic waves. This was obtained from the leakage in a microfluidic channel of two standing waves arranged perpendicularly in a LiNbO3 piezoelectric substrate working at 36.3 MHz. By controlling the phase lag between the emitters, we could, in addition to translation, generate a swirling motion of the emitting surface which, in turn, led to the rapid rotation of spherical polystyrene Janus beads suspended in the channel and of human red and white blood cells up to several rounds per second. We show that these revolution velocities are compatible with a torque caused by the acoustic streaming that develops at the particles surface, like that first described by [F. Busse et al., J. Acoust. Soc. Am., 1981, 69 (6), 1634–1638]. This device, based on standard interdigitated transducers (IDTs) adjusted to emit at equal frequencies, opens a way to a large range of applications since it allows the simultaneous control of the translation and rotation of hard objects, as well as the investigation of the response of cells to shear stress.