A membrane-anchored aptamer sensor for probing IFNγ secretion by single cells. Issue 57 (4th July 2017)

• Record Type: Journal Article
• Authors: Qiu, Liping; Wimmers, Florian; Weiden, Jorieke; Heus, Hans A.; Tel, Jurjen; Figdor, Carl G.
• Is Part Of: Chemical communications. Volume 53:Issue 57(2017)
• Page Start: 8066
• Page End: 8069
• Publication Date: 2017-07-04
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc03576d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. Abstract : Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. In this work, we have developed a cell membrane-anchored sensor for the detection of cytokines secreted by single cells using a combination of aptamer-based sensors and droplet microfluidics.