Sensitive determination of chlorogenic acid in pharmaceutical products based on the decoration of 3D macroporous carbon with Au nanoparticles via polyoxometalates. Issue 14 (12th June 2017)

• Record Type: Journal Article
• Authors: Zhang, Tongrui; Liu, Mengjun; Zhang, Qianqian; Wang, Yeyu; Kong, Xiangyi; Wang, Lei; Wang, Huan; Zhang, Yufan
• Is Part Of: Analyst. Volume 142:Issue 14(2017)
• Page Start: 2603
• Page End: 2609
• Publication Date: 2017-06-12
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c7an00493a
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : A simple and sensitive electrochemical sensor is constructed for the detection of chlorogenic acid (CGA). Abstract : A simple and sensitive electrochemical sensor is constructed for the detection of chlorogenic acid (CGA) based on Au nanoparticles (NPs)/polyoxometalates/3D macroporous carbon (Au-POMs-MPC). Serving as both a reducing and stabilizing agent, the Keggin-type POM, H3 PW12 O40, is used for the synthesis of stable colloidal Au NPs and then used to link them to MPC at a mild temperature. Because of the unique structural properties and synergetic catalytic effect, Au-POMs-MPC can be developed as an effective sensing platform for the detection of CGA, which showed high activity and excellent analytical performance towards CGA, such as a wide linear range of 2.28 nM–3.24 μM, a high sensitivity of 30 554.71 μA mM −1, and a low limit of detection of 2.15 nM. Importantly, the successfully fabricated Au-POMs-MPC device accurately measured the amount of CGA in pharmaceutical samples.