Ficusnotins A–F: Rare diarylbutanoids from the leaves of Ficus nota. (September 2017)

• Record Type: Journal Article
• Authors: Latayada, Felmer S.; Uy, Mylene M.; Akihara, Yui; Ohta, Emi; Nehira, Tatsuo; Ômura, Hisashi; Ohta, Shinji
• Is Part Of: Phytochemistry. Volume 141(2017)
• Page Start: 98
• Page End: 104
• Publication Date: 2017-09
• Subjects: Ficus nota -- Moraceae -- Diarylbutanoid -- Ficusnotin A–F -- Antibacterial activity; Botanical chemistry -- Periodicals; Biochemistry -- Periodicals; Botany -- Periodicals; Chimie végétale -- Périodiques; 572.2
• DOI: 10.1016/j.phytochem.2017.05.016
• Languages: English
• ISSNs: 0031-9422

Abstract

Abstract: Six diarylbutanoids, designated as ficusnotins A–F, with a rare carbon skeleton consisting of two aromatic rings separated by an unbranched C4-chain have been isolated from the leaves of Ficus nota (Blanco) Merr. (Moraceae). The structures were determined on the basis of spectroscopic data, as well as X-ray crystallographic analysis. The isolated compounds were evaluated for their antibacterial activity against Bacillus subtilis . Graphical abstract: Six diarylbutanoids were isolated from the leaves of Ficus nota (Blanco) Merr. (Moraceae) and the structures were determined based on spectroscopic data as well as X-ray diffraction analysis. Their antibacterial activity was evaluated. Highlights: Six 1, 4-diarylbutanoids were isolated from leaves of Ficus nota . The structures were characterized by spectroscopic methods and X-ray analysis. The biogenetic pathway to the compounds was proposed.