Study on the interaction between gelatin and polyurethanes derived from fatty acids1. Issue 4 (11th September 2012)

• Record Type: Journal Article
• Authors: González‐Paz, R. J.; Lligadas, G.; Ronda, J. C.; Galià, M.; Ferreira, A. M.; Boccafoschi, F.; Ciardelli, G.; Cádiz, V.
• Is Part Of: Journal of biomedical materials research. Volume 101A:Issue 4(2013:May)
• Page Start: 1036
• Page End: 1046
• Publication Date: 2012-09-11
• Subjects: polyurethane -- fatty acid -- gelatin -- blend -- bioactivity -- immunocytochemistry; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/jbm.a.34407
• Languages: English
• ISSNs: 1549-3296

Abstract

Abstract: In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2013.