Immune Reconstitution Syndrome secondary to Rhodococcus equi infection in a patient with HIV and Burkitt's lymphoma. Issue 2 (March 2017)

• Record Type: Journal Article
• Authors: Darraj, Majid; Fainstein, Rachel; Kasper, Ken; Keynan, Yoav
• Is Part Of: Journal of infection and public health. Volume 10:Issue 2(2017)
• Page Start: 224
• Page End: 227
• Publication Date: 2017-03
• Subjects: Human immunodeficiency virus -- Rhodococcus equi -- Burkitt's lymphoma -- Cavitating pneumonia; Communicable diseases -- Periodicals; Public health -- Periodicals; Epidemiology -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Medical microbiology -- Periodicals; 614.4
• DOI: 10.1016/j.jiph.2016.05.001
• Languages: English
• ISSNs: 1876-0341

Abstract

Summary: Immune Reconstitution Syndrome (IRIS) has been associated with a variety of infections in patients with human immunodeficiency virus (HIV). However, we are reporting the first case of IRIS secondary to Rhodococcus equi ( R. equi ) in a patient with HIV. We report the case of a 48-year-old male found to have HIV infection in the setting of Burkitt's lymphoma. While on anti-retroviral therapy and chemotherapy, he had developed IRIS secondary to R. equi that manifested as a cavitating pneumonia. This report outlines the successful management of the R. equi infection with the use of a combination of antibiotics, radiographic follow up and suppressive antibiotic while on chemotherapy.