Nomenclature and definition in asymmetric regional body overgrowth. Issue 7 (5th May 2017)

• Record Type: Journal Article
• Authors: Kalish, Jennifer M.; Biesecker, Leslie G.; Brioude, Frederic; Deardorff, Matthew A.; Di Cesare‐Merlone, Alessandra; Druley, Todd; Ferrero, Giovanni B.; Lapunzina, Pablo; Larizza, Lidia; Maas, Saskia; Macchiaiolo, Marina; Maher, Eamonn R.; Maitz, Silvia; Martinez‐Agosto, Julian A.; Mussa, Alessandro; Robinson, Peter; Russo, Silvia; Selicorni, Angelo; Hennekam, Raoul C.
• Is Part Of: American journal of medical genetics. Volume 173:Issue 7(2017)
• Page Start: 1735
• Page End: 1738
• Publication Date: 2017-05-05
• Subjects: Beckwith‐Wiedemann syndrome -- isolated hemihyperplasia -- isolated hemihypertrophy -- isolated lateralized overgrowth -- isolated unilateral overgrowth -- lateralized overgrowth -- segmental overgrowth; Medical genetics -- Periodicals; 616.14205
• DOI: 10.1002/ajmg.a.38266
• Languages: English
• ISSNs: 1552-4825

Abstract

Abstract : We designate a novel term "isolated lateralized overgrowth" (ILO) for the findings previously described as "isolated hemihypertrophy" and "isolated hemihyperplasia." ILO is defined as lateralized overgrowth in the absence of a recognized pattern of malformations, dysplasia, or morphologic variants. ILO is likely genetically heterogeneous. Further study is required to determine more of the underlying genetic etiologies and potential associations with currently unrecognized patterns of malformation.