Asymmetric cross- and self-aldol reactions of aldehydes in water with a polystyrene-supported triazolylproline organocatalyst. Issue 12 (11th May 2016)

• Record Type: Journal Article
• Authors: Llanes, Patricia; Sayalero, Sonia; Rodríguez-Escrich, Carles; Pericàs, Miquel A.
• Is Part Of: Green chemistry. Volume 18:Issue 12(2016)
• Page Start: 3507
• Page End: 3512
• Publication Date: 2016-05-11
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c6gc00792a
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : A PS-immobilized triazolylproline prepared by co-polymerization with full regiocontrol swells in water and catalyzes the enantioselective cross-aldol reaction and the self-aldol reaction of aldehydes under essentially neat conditions with excellent stereocontrol. Abstract : A polystyrene (PS) immobilized triazolylproline has been prepared by a bottom-up approach involving co-polymerization with full regiocontrol. The resulting PS resin swells in water and has been applied to the enantioselective cross-aldol reaction and to the self-aldol reaction of aldehydes under essentially neat conditions, excellent yields and stereoselectivities being recorded.