Repetitive formation of optically-observable planar lipid bilayers by rotating chambers on a microaperture. Issue 13 (3rd June 2016)

• Record Type: Journal Article
• Authors: Tomoike, Fumiaki; Tonooka, Taishi; Osaki, Toshihisa; Takeuchi, Shoji
• Is Part Of: Lab on a chip. Volume 16:Issue 13(2016)
• Page Start: 2423
• Page End: 2426
• Publication Date: 2016-06-03
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/c6lc00363j
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : Rotational chambers are applied for painting lipids to the aperture, enabling us to observe the repetitive formation of optically-observable lipid bilayers. Abstract : Optical observation of a planar lipid bilayer is an effective method of lipid bilayer characterization. However, previous methods for optically observable lipid bilayer formation are unsuitable for repetitive formation of lipid bilayers. In this paper, we propose a system that facilitates repetitive formation of horizontal lipid bilayers via mechanical rotation of the rotating part. We show that multiple bilayers can be observed within a short period, and that the electrical and optical characteristics of a bilayer can be analyzed simultaneously.