Cancer‐related fatigue and its impact on functioning. (20th May 2013)

• Record Type: Journal Article
• Authors: Minton, Ollie; Berger, Ann; Barsevick, Andrea; Cramp, Fiona; Goedendorp, Martine; Mitchell, Sandra A.; Stone, Patrick C.
• Is Part Of: Cancer. Volume 119(2013)Supplement 11
• Page Start: 2124
• Page End: 2130
• Publication Date: 2013-05-20
• Subjects: cancer‐related fatigue -- neoplasms -- survivors -- interventions; Cancer -- Periodicals; Cancer -- Cytopathology -- Periodicals; 616.99405
• DOI: 10.1002/cncr.28058
• Languages: English
• ISSNs: 0008-543X

Abstract

Abstract : This article presents the contrasting European and American perspectives on cancer‐related fatigue (CRF) and its impact on functioning in cancer survivors. The content is presented in 3 sections: state of the art, intervention studies, and future areas of research, followed by a discussion. Gaps identified include a lack of understanding of the etiology, definition, and measurement of CRF. Models to guide the study of CRF, selection of biomarkers, and design of interventions are needed. There is overlap between Europe and the United States concerning the future directions for research and collaboration related to CRF. The authors suggest the need for international consensus regarding the defining features of CRF in cancer survivors to identify phenotypes, a harmonized measurement of CRF outcomes using instruments that have demonstrated measurement equivalence across languages and cultures, and interventions (including exercise, rehabilitation, and psychoeducational) that have been manualized to permit intervention fidelity across diverse contexts. Coordinated intercontinental efforts would increase understanding of the biological, psychological, and social mechanisms underlying CRF and assist in the design of future intervention studies as well as revisions to clinical guidelines. Cancer 2013;119(11 suppl):2124‐30. © 2013 American Cancer Society . Abstract : This article presents the contrasting European and American perspectives on cancer‐related fatigue and its impact on functioning in survivors with regard to 3 sections (state of the art, intervention studies, and future areas of research), as well as research gaps and future directions for research and collaboration related to fatigue. Coordinated intercontinental efforts would increase understanding of the biological, psychological, and social mechanisms underlying fatigue and assist in future intervention studies as well as revisions to clinical guidelines.