Convenient Synthesis of Arylboronates through a Synergistic Pd/Cu‐Catalyzed Miyaura Borylation Reaction under Atmospheric Conditions. Issue 7 (28th January 2014)

• Record Type: Journal Article
• Authors: Ratniyom, Jadsada; Dechnarong, Nattanee; Yotphan, Sirilata; Kiatisevi, Supavadee
• Is Part Of: European journal of organic chemistry. Issue 7(2014)
• Page Start: 1381
• Page End: 1385
• Publication Date: 2014-01-28
• Subjects: Boron -- Palladium -- Copper -- Cross‐coupling -- Atmospheric conditions; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201301634
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: A highly efficient and practical borylation reaction of aryl iodides with bis(pinacolato)diboron has been established. By using Pd(OAc)2, CuI, and PPh3 as a ligand at room temperature under air in the presence of Cs2 CO3, the protocol proved to be general. Various functionalized arylboronates were obtained in moderate to excellent yields. In addition, a possible reaction mechanism was proposed. Abstract : An efficient borylation reaction of aryl iodides with bis(pinacolato)diboron is developed by using Pd(OAc)2 and CuI. This catalytic system has high catalytic efficiency at room temperature in air and functional‐group tolerance for a wide range of substrates.