Pharmacogenetic Implementation Lessons From the "Real World". Issue 1 (25th March 2017)

• Record Type: Journal Article
• Authors: Roden, DM
• Is Part Of: Clinical pharmacology & therapeutics. Volume 102:Issue 1(2017)
• Page Start: 25
• Page End: 27
• Publication Date: 2017-03-25
• Subjects: Pharmacology -- Periodicals; Therapeutics -- Periodicals; 615.5
• DOI: 10.1002/cpt.584
• Languages: English
• ISSNs: 0009-9236

Abstract

Abstract : The manuscript "Anticoagulation Endpoints With Clinical Implementation of Warfarin Pharmacogenetic Dosing in a Real‐ World Setting: A Proposal for a New Pharmacogenetic Dosing Approach" describes process outcomes in an institutional program to use pharmacogenetic testing to optimize warfarin dose in a cohort of 257 patients of diverse ancestries. The strengths and weaknesses of the approach and program are discussed, along with the current and potential future status of warfarin as a model for pharmacogenetic testing.