Acetylene as a Driving and Organizing Molecule in One‐Pot Transition‐Metal‐Free Synthesis of Furans using Chalcones and their Analogues. Issue 6 (24th April 2017)

• Record Type: Journal Article
• Authors: Trofimov, Boris A.; Bidusenko, Ivan A.; Schmidt, Elena Yu.; Ushakov, Igor' A.; Vashchenko, Alexander V.
• Is Part Of: Asian journal of organic chemistry. Volume 6:Issue 6(2017)
• Page Start: 707
• Page End: 711
• Publication Date: 2017-04-24
• Subjects: acetylenes -- C−C bond formation -- chalcones -- furans -- superbases; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201700085
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: Acetylene reacts with chalcones and their heterocyclic analogues in NaO t Bu/DMSO catalytic system (70 °C, 15 min) to afford substituted furans in a yield of up to 85 %, thus providing a simple and technologically feasible access to rare furan compounds. Abstract : Basic approach : A simple NaO t Bu/DMSO catalytic system is used for the synthesis of substituted furan compounds using acetylenes and chalcone derivatives. A yield of up to 85 % was obtained for the furan products.