First report of the ceftazidimase CTX‐M‐19 in South America. Issue 3 (22nd December 2013)

• Record Type: Journal Article
• Authors: García‐Fulgueiras, V.; Bado, I.; Cordeiro, N. F.; Algorta, G.; Vignoli, R.
• Is Part Of: New microbes and new infections. Volume 1:Issue 3(2013)
• Page Start: 44
• Page End: 47
• Publication Date: 2013-12-22
• Subjects: Ceftazidimase -- CTX‐M‐19 -- ESBL -- IS26 -- IS903; Medical microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; Microbiology -- Periodicals; Communicable Diseases -- Periodicals; Infection -- Periodicals; 616.9041
• DOI: 10.1002/nmi2.25
• Languages: English
• ISSNs: 2052-2975

Abstract

Abstract: We report the first detection of bla CTX‐M‐19 in South America, harboured in an Escherichia coli isolate obtained from a urine sample; such an isolate belonged to phylogenetic group A, ST603, and showed a ceftazidimase profile. bla CTX‐M‐19 was encoded in an approximately 100 kb IncI1/IncF conjugative plasmid, featuring pndAC and hok / sok addiction systems; the β ‐lactamase gene was flanked upstream by three tandem‐like transposons (IS 26, IS 10 and IS Ecp1 ), inserted one inside the other, and downstream by IS 903 .