New naphthalene derivative from the leaves of Cassia grandis L. Issue 15 (3rd August 2017)

• Record Type: Journal Article
• Authors: Trinh, Pham Thi Nhat; Luan, Ngoc Quoc; Tri, Mai Dinh; Khanh, Vu Duy; An, Nguyen Huu; Minh, Phan Nhat; An, Pham Ngoc; Thuy, Nguyen Thi Le; Phung, Nguyen Kim Phi; Dung, Le Tien
• Is Part Of: Natural product research. Volume 31:Issue 15(2017)
• Page Start: 1733
• Page End: 1738
• Publication Date: 2017-08-03
• Subjects: Cassgranon D -- Cassia grandis -- naphthalene derivative; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2017.1290615
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2 ), afzelin (3 ), quercitrin (4 ), epicatechin (5 ), (-)-epiafzelechin (6 ), isoquercitrin (7 ) and aloe emodin (8 ) were isolated from the ethyl acetate and methanol extracts. Their structures were elucidated by spectral evidences (UV, IR, MS, 1 H, 13 C, DEPT, HSQC and HMBC NMR), as well as by comparing with published data. Abstract :