Copper(II)‐Catalyzed Aromatization Followed by Bromination of Cyclohexenones Leading to Phenols and Bromophenols. Issue 15 (11th April 2014)

• Record Type: Journal Article
• Authors: Tong, Hung‐Chun; Reddy, K. Rajender; Liu, Shiuh‐Tzung
• Is Part Of: European journal of organic chemistry. Issue 15(2014)
• Page Start: 3256
• Page End: 3261
• Publication Date: 2014-04-11
• Subjects: Aromatization -- Copper -- Bromination­ -- Homogenous catalysis -- Oxidation­ -- Aromatic substitution; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201400158
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: Conversion of substituted cyclohexenones into the corresponding phenols can be achieved using copper acetate as the catalyst in the presence of LiBr and CF3 COOH under oxygen. With the use of excess LiBr, electrophilic aromatic bromination afforded the corresponding bromophenol under similar catalytic conditions. Abstract : Conversion of substituted cyclohexenones into corresponding phenols and/or bromophenols can be achieved using copper acetate as the catalyst in the presence of LiBr and CF3 COOH under oxygen.