Brainstem micro-abscesses caused by Burkholderia pseudomallei in a 10-month-old infant: a case report. (3rd July 2017)

• Record Type: Journal Article
• Authors: Prasanna Kumar, M.; Krishnamurthy, Sriram; Venkateswaran, V. S.; Mahadevan, Subramanian; Lalitha, M.; Sistla, Sujatha; Nagarajan, K.
• Is Part Of: Paediatrics and international child health. Volume 37:Number 3(2017)
• Page Start: 230
• Page End: 232
• Publication Date: 2017-07-03
• Subjects: Neuromelioidosis -- Infant -- Burkholderia pseudomallei -- Brainstem micro-abscesses -- Melioidosis; Pediatrics -- Developing countries -- Periodicals; Children -- Health and hygiene -- Developing countries -- Periodicals; Children -- Diseases -- Developing countries -- Periodicals; 618.920009172405
• DOI: 10.1080/20469047.2016.1198560
• Languages: English
• ISSNs: 2046-9047

Abstract

Abstract : Melioidosis is an uncommon tropical infectious disease caused by Burkholderia pseudomallei . Neurological complications of melioidosis are extremely uncommon in infants. A 10-month-old girl is described who presented with disseminated melioidosis with subcutaneous nodules, arthritis, hepatomegaly and a lung cavity, and developed a left medial rectus palsy. Cranial MRI demonstrated mid-brain, pontine and basal ganglia micro-abscesses. Therapy with meropenem and cotrimoxazole led to resolution of the medial nerve palsy. At 5-month follow-up, the child had no residual neurological deficits.