Recent advances in N-heterocyclic carbene catalyzed achiral synthesis. Issue 22 (25th May 2017)

• Record Type: Journal Article
• Authors: Ren, Qiao; Li, Muyao; Yuan, Lujiang; Wang, Jian
• Is Part Of: Organic & biomolecular chemistry. Volume 15:Issue 22(2017)
• Page Start: 4731
• Page End: 4749
• Publication Date: 2017-05-25
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob00568g
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : This review reveals the recent developments in NHC-promoted non-asymmetric umpolung transformations resulting in the expeditious construction of versatile achiral natural heterocycles, carbocycles and acylated products. Abstract : N-Heterocyclic carbenes (NHCs) have emerged as powerful and elegant organocatalysts in a variety of newly developed and unprecedented enantioselective transformations due to their unique umpolung capacity. As a supplement to conventional enantioselective organocatalysis, NHC-induced non-asymmetric catalysis has gradually attracted much interest in recent years. Herein, this review aims to reveal the recent developments in NHC-promoted non-asymmetric umpolung transformations resulting in the expeditious construction of versatile achiral natural heterocycles, carbocycles and acylated products.