Direct C–C Bond Construction from Arylzinc Reagents and Aryl Halides without External Catalysts. Issue 35 (5th November 2013)

• Record Type: Journal Article
• Authors: Minami, Hiroki; Wang, Xuan; Wang, Chao; Uchiyama, Masanobu
• Is Part Of: European journal of organic chemistry. Issue 35(2013)
• Page Start: 7891
• Page End: 7894
• Publication Date: 2013-11-05
• Subjects: Cross‐coupling -- Organozinc compounds -- Halides -- C–C bond formation -- Biaryls; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201301404
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: Direct cross‐coupling between an arylzinc reagent and an aryl halide was accomplished without any external catalyst, enabling efficient and selective formation of the corresponding biaryl compound with broad functional group compatibility. Abstract : Direct cross‐coupling between a diarylzinc compound and an aryl iodide was accomplished without using any external catalyst. The reaction is efficient and selective, enabling formation of the corresponding biaryl compounds with broad functional group compatibility. The reaction is proposed to proceed by a thermally initiated single electron transfer (SET) route.