BF3·OEt2‐Promoted Tandem O‐Arylation/Hydroxylation: Efficient Synthesis of 2‐Hydroxyflavanones from Triazenylaryl‐Substituted Diketones. Issue 32 (25th September 2013)

• Record Type: Journal Article
• Authors: Chen, Zhengkai; Yang, Weijun; Xu, Lijun; Zhang, Lili; Miao, Maozhong; Ren, Hongjun
• Is Part Of: European journal of organic chemistry. Issue 32(2013)
• Page Start: 7411
• Page End: 7420
• Publication Date: 2013-09-25
• Subjects: Synthetic methods -- Nucleophilic substitution -- Arylation -- Cycliza­tion -- Triazenes -- Lewis acids; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201300966
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: A transition‐metal‐free tandem O ‐arylation/hydroxylation approach has been developed for the efficient synthesis of highly substituted 2‐hydroxyflavanones from triazenylaryl‐substituted diketones. The intermediate benzopyrylium cation may be involved in these reactions. Abstract : Highly substituted 2‐hydroxyflavanones can be obtained through a tandem O ‐arylation/hydroxylation process from triazenylaryl‐substituted diketones in the presence of a Lewis acid.