An expedient E-stereoselective synthesis of multi-substituted functionalized allylic boronates from Morita–Baylis–Hillman alcohols. Issue 7 (11th May 2017)

• Record Type: Journal Article
• Authors: Xuan, Qingqing; Wei, Yahui; Chen, Jinglong; Song, Qiuling
• Is Part Of: Organic chemistry frontiers. Volume 4:Issue 7(2017)
• Page Start: 1220
• Page End: 1223
• Publication Date: 2017-05-11
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c7qo00253j
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Various functionalized tri-substituted allylic boronates were synthesized through borylation of Morita–Baylis–Hillman alcohols under the catalysis of Cu(OTf)2 at ambient temperature. Abstract : An expedient and stereoselective synthesis of functionalized trisubstituted allylic boronates via direct borylation of Morita–Baylis–Hillman alcohols is disclosed. The reaction proceeds smoothly at ambient temperature with high atomic and synthetic efficiency. The desired allylic boronates can be applied in the efficient synthesis of homoallyl alcohols and α-exomethylene γ-lactones.