The influence of polydopamine coating on gold nanorods for laser desorption/ionization time-of-flight mass spectrometric analysis. Issue 13 (2nd June 2017)

• Record Type: Journal Article
• Authors: Kang, Kyungtae; Jang, Hongje; Kim, Young-Kwan
• Is Part Of: Analyst. Volume 142:Issue 13(2017)
• Page Start: 2372
• Page End: 2377
• Publication Date: 2017-06-02
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c7an00356k
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : The influence of polydopamine (PD) coating on gold nanorods (GNRs) for laser desorption/ionization mass spectrometry (LDI-MS) analysis was systematically investigated to reveal its role in the LDI-MS analysis process. Abstract : This paper examines the effect of polydopamine (PD) coating of gold nanorods (GNRs) on their performance as a matrix material for laser desorption/ionization time-of-flight mass spectrometry (LDI-TOF-MS) analysis. Bare GNRs and PD-coated GNRs (PD@GNRs) were utilized for LDI-TOF-MS analyses of small molecules and synthetic polymers, and the influences of PD-coating were mechanistically studied. Based on the results, we found that the PD-coating of GNRs suppressed the generation of undesired gold cluster ions, enhanced photothermal conversion and the LDI-TOF-MS efficiency, and expanded the working molecular weight range.