Continuous flow dynamic kinetic resolution of rac-1-phenylethanol using a single packed-bed containing immobilized CAL-B lipase and VOSO4 as racemization catalysts. Issue 3 (1st March 2017) - de Miranda, Amanda S.
Abstract : Herein, we report a method for the continuous flow DKR of rac -1-phenylethanol catalyzed by CAL-B and VOSO4, using a single packed-bed containing both catalysts. Abstract : Herein, we report a method for the continuous flow DKR of rac -1-phenylethanol catalyzed by CAL-B and VOSO4, using a single packed-bed containing both catalysts. Taking advantage of continuous flow techniques to circumvent compatibility issues, the DKR of rac -1-phenylethanol could be performed continuously to give enantiopure ( R )-esters with excellent conversions and high productivities.