Cesium Carbonate Mediated Borylation of Aryl Iodides with Diboron in Methanol. Issue 28 (22nd August 2013)

• Record Type: Journal Article
• Authors: Zhang, Jieming; Wu, Hai‐Hong; Zhang, Junliang
• Is Part Of: European journal of organic chemistry. Issue 28(2013)
• Page Start: 6263
• Page End: 6266
• Publication Date: 2013-08-22
• Subjects: Transition metals -- Copper -- ­Cesium -- Boron -- Lewis bases; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201300829
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: Herein we describe the unexpected borylation of aryl iodides promoted by a Cs2 CO3 and MeOH system. This formal nucleophilic boryl substitution could be applied to a wide range of functionalized aryl iodide compounds. The preliminary results indicate that this process is neither copper catalyzed nor radical mediated. Abstract : Transition‐metal free! The unexpected borylation of aryl iodides promoted by Cs2 CO3 and MeOH is revealed. This formal nucleophilic boryl substitution can be applied to a wide range of functionalized aryl iodide compounds. The preliminary results indicate that this process is neither copper catalyzed nor radical mediated (pin = pinacolato, OCMe2 CMe2 O; neop = neopentylglycolato, OCH2 CMe2 CH2 O).