Palladium-catalyzed arene C–H activation/ketone C–H functionalization reaction: route to spirodihydroindenones. Issue 7 (24th April 2017)

• Record Type: Journal Article
• Authors: Zhang, Bo-Sheng; Hua, Hui-Liang; Gao, Lu-Yao; Liu, Ce; Qiu, Yi-Feng; Zhou, Ping-Xin; Zhou, Zhao-Zhao; Zhao, Jia-Hui; Liang, Yong-Min
• Is Part Of: Organic chemistry frontiers. Volume 4:Issue 7(2017)
• Page Start: 1376
• Page End: 1379
• Publication Date: 2017-04-24
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c7qo00164a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A novel palladium and norbornene catalyzed arene C–H activation method to synthesize various spirodihydroindenone derivatives is developed. Abstract : A novel palladium and norbornene catalyzed arene C–H activation method to synthesize various spirodihydroindenone derivatives was developed. This method produces spirodihydroindenones employing aryl iodides with 2-(2-bromoethyl)-cyclopentanones via a domino reaction, which simplifies the route of building spiro compounds and expands further applications for functional groups selectivity.